{"id":5265,"date":"2021-01-29T22:18:36","date_gmt":"2021-01-29T21:18:36","guid":{"rendered":"https:\/\/www.fipwarriors.eu\/?p=5265"},"modified":"2023-03-29T09:50:20","modified_gmt":"2023-03-29T07:50:20","slug":"historia-studia-infekcnej-peritonitidy-maciek","status":"publish","type":"post","link":"https:\/\/www.fipwarriors.eu\/en\/historia-studia-infekcnej-peritonitidy-maciek\/","title":{"rendered":"History of feline infectious peritonitis studies"},"content":{"rendered":"

Pôvodný článok: UC Davis has long history of studying feline infectious peritonitis<\/a><\/p>\n\n\n\n

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Smokey<\/figcaption><\/figure><\/div>\n\n\n\n

Výskum mačacej infekčnej peritonitídy (FIP<\/a>) na UC Davis začal v roku 1964 Dr. Niels Pedersen, ktorý bol v tom čase študent veterinárneho lekárstva, a Dr. Billy Ward, v tom čase absolvent veterinárnej patológie. Pedersen sa neskôr stal profesorom medicíny a epidemiológie a zakladajúcim riaditeľom CCAH.<\/p>\n\n\n\n

Ward a Pedersen publikovali svoje výskumy týkajúce sa FIP v roku 1969. Pedersen sa o túto chorobu zaujímal aj počas svojej stáže na Colorado State University a doktorandského štúdia na Austrálskej národnej univerzite. Aktívne pokračoval vo výskume FIP a iných infekčných chorôb mačiek po návrate na UC Davis a na veterinárnu školu v roku 1972. Výskumný program FIP je na UC aktívny dodnes.<\/p>\n\n\n\n

Pedersen je svetovo uznávanou autoritu v oblasti FIP a má na svojom konte 45 významných vedeckých článkov a množstvo kapitol a recenzií vo veterinárnej literatúre. Jeho učebnica „Chov mačiek, choroby a manažment v prostredí s viacerými mačkami“ je medzi chovateľmi stále považovaná za klasiku. Pedersen odišiel do dôchodku v roku 2013, naďalej však pokračuje v aktívnom výskumnom programe FIP ako emeritný profesor. Doterajší výskum sa naďalej zameriava na to, ako FIPV spôsobuje samotnú chorobu, genetické a environmentálne faktory ovplyvňujúce výskyt choroby, a najnovšie na použitie špecifických liekov zameraných na replikáciu FIPV u mačiek.<\/p>\n\n\n\n

Pedersen je šťastný, že mal podporu súkromných organizácií, ako sú Winn Feline Foundation, Morris Animal Foundation, Save Our Cats and Kittens (SOCK) a SOCK FIP, súkromné nadácie a registre čistokrvných mačiek, a mnoho individuálnych darcov. „Keďže sa moja kariéra chýli ku koncu, je pre mňa veľkým potešením, že sa ku mne pripojili moji kolegovia, vrátane Dr. Briana Murphyho a Dr. Patty Pesavento, ktorí prispievajú k udržaniu reputácie Školy veterinárneho lekárstva ako jednej z popredných výskumných skupín koronavírusových infekcií mačiek, ako sú FECV a FIPV, “hovorí Pedersen. „Všetci sa zhodneme v tom, že FIP je jednou z najkomplexnejších infekčných chorôb ľudí a zvierat.“ Našťastie však Pedersenov viac ako polstoročný výskum pomohol odhaliť veľkú časť tejto zložitej skladačky. <\/p>\n\n\n\n

Mnoho kľúčových objavov ohľadne FIP pochádza z našej školy a Pedersenovho laboratória, vrátane prvého rozmonoženia koronavírusu v tkanivovej kultúre, rozpoznania jeho vzťahu k bežným koronavírusom iných druhov, vývoja testu na protilátky<\/a> pre mačací koronavírus a objav, že vírus FIP (FIPV) je neobvyklou mutáciou všadeprítomného a väčšinou nepatogénneho mačacieho enterického koronavírusu (FECV). Pokusy vyvinúť vakcíny proti tejto chorobe zlyhali, čo viedlo k štúdiu toho, ako znížiť výskyt choroby v chovných staniciach, útulkoch a iných vysoko rizikových prostrediach pomocou preventívnych opatrení pri chove mačiek. Dr. Pedersen tiež dokončil niekoľko štúdií o úlohe dedičných faktorov pri predispozícii na FIP. Zistilo sa, že genetická citlivosť a rezistencia sú veľmi zložité a pokusy o zvýšenie rezistencie selektívnym šľachtením prirodzene imúnnych samíc a samcov viedli skôr k zvýšenej, než zníženej náchylnosti. Zistilo sa, že hlavným dedičným rizikovým faktorom je príbuzenské kríženie.<\/p>\n\n\n\n

Mačky, ktoré prežili FIP<\/h5>\n\n\n\n
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\"\"<\/a>
Luna<\/figcaption><\/figure>\n<\/div>\n\n\n\n
\n
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Bubba<\/figcaption><\/figure>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Article from the UC Davis website about the history of FIP and its research. dr. Pedersen began researching FIP at UC Davis in 1964, and his life's work culminated in the discovery of a cure for this dreaded disease. <\/p>","protected":false},"author":1,"featured_media":5274,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_uag_custom_page_level_css":"","footnotes":""},"categories":[187,188],"tags":[],"class_list":["post-5265","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-odborne","category-preverejnost"],"featured_image_urls_v2":{"full":["https:\/\/www.fipwarriors.eu\/wp-content\/uploads\/2021\/01\/black-cat-faceFHD.jpg",1920,1080,false],"thumbnail":["https:\/\/www.fipwarriors.eu\/wp-content\/uploads\/2021\/01\/black-cat-faceFHD-150x150.jpg",150,150,true],"medium":["https:\/\/www.fipwarriors.eu\/wp-content\/uploads\/2021\/01\/black-cat-faceFHD-300x169.jpg",300,169,true],"medium_large":["https:\/\/www.fipwarriors.eu\/wp-content\/uploads\/2021\/01\/black-cat-faceFHD-768x432.jpg",525,295,true],"large":["https:\/\/www.fipwarriors.eu\/wp-content\/uploads\/2021\/01\/black-cat-faceFHD-1024x576.jpg",525,295,true],"1536x1536":["https:\/\/www.fipwarriors.eu\/wp-content\/uploads\/2021\/01\/black-cat-faceFHD-1536x864.jpg",1536,864,true],"2048x2048":["https:\/\/www.fipwarriors.eu\/wp-content\/uploads\/2021\/01\/black-cat-faceFHD.jpg",1920,1080,false],"trp-custom-language-flag":["https:\/\/www.fipwarriors.eu\/wp-content\/uploads\/2021\/01\/black-cat-faceFHD-16x9.jpg",16,9,true],"twentyseventeen-featured-image":["https:\/\/www.fipwarriors.eu\/wp-content\/uploads\/2021\/01\/black-cat-faceFHD.jpg",1920,1080,false],"twentyseventeen-thumbnail-avatar":["https:\/\/www.fipwarriors.eu\/wp-content\/uploads\/2021\/01\/black-cat-faceFHD-100x100.jpg",100,100,true],"woocommerce_thumbnail":["https:\/\/www.fipwarriors.eu\/wp-content\/uploads\/2021\/01\/black-cat-faceFHD-250x250.jpg",250,250,true],"woocommerce_single":["https:\/\/www.fipwarriors.eu\/wp-content\/uploads\/2021\/01\/black-cat-faceFHD-350x197.jpg",350,197,true],"woocommerce_gallery_thumbnail":["https:\/\/www.fipwarriors.eu\/wp-content\/uploads\/2021\/01\/black-cat-faceFHD-100x100.jpg",100,100,true]},"post_excerpt_stackable_v2":"

Článok z webu UC Davis o histórii FIP<\/a> a jej výskumu. Dr. Pedersen začal výskum FIP na UC Davis v roku 1964 a jeho celoživotné dielo bolo zakončené objavom liečby tejto obávanej choroby. <\/p>\n","category_list_v2":"Odborn\u00e9<\/a>, Pre verejnos\u0165<\/a>","author_info_v2":{"name":"LM","url":"https:\/\/www.fipwarriors.eu\/en\/author\/starman\/"},"comments_num_v2":"0 comments","featured_image_src":"https:\/\/www.fipwarriors.eu\/wp-content\/uploads\/2021\/01\/black-cat-faceFHD.jpg","author_info":{"display_name":"L. M.","author_link":"https:\/\/www.fipwarriors.eu\/en\/author\/starman\/"},"yoast_head":"\nHist\u00f3ria \u0161t\u00fadia infek\u010dnej peritonit\u00eddy ma\u010diek - FIP Warriors CZ\/SK \u00ae<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.fipwarriors.eu\/en\/historia-studia-infekcnej-peritonitidy-maciek\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hist\u00f3ria \u0161t\u00fadia infek\u010dnej peritonit\u00eddy ma\u010diek - FIP Warriors CZ\/SK \u00ae\" \/>\n<meta property=\"og:description\" content=\"Článok z webu UC Davis o histórii FIP a jej výskumu. 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