Introduction

Welcome to the FIP Warriors site, where we would like to bring you information about FIP treatment - a disease that until recently meant a death sentence for every cat that it broke out of. The hope for rescue came with an nucleoside analog GS-441524 developed by Gilead Sciences, where the GS code name comes from.

The discovery of FIP treatment was the culmination of 50 years of research of Dr. Pedersen and his team. In 2017 there took place at UC Davis under his leadership field trials using a new substance, which at that time was still known as EVO984. As a result, its efficacy in the treatment of this dreaded disease was clearly confirmed. So the stories of the FIP warriors began to be written, which finally began to win over the disease.

Given that the patent owner of Gilead Sciences is not interested in launching GS-441524, and especially in relation to Covid-19, he preferred Remdesivir, it is very questionable when and if we will ever receive legal treatment in the foreseeable future. All medicines on the market are thus produced without the consent of Gilead and come from the Chinese market. We would like to draw your attention to the fact that if you use any information that you learn here in practice, you do so at your own risk. By staying on this site, you agree to this basic condition. We thank you.

Základné otázky

What is FIP

Feline infectious peritonitis (FIP) is a fatal infectious disease of cats. There are two basic forms - wet (effusive) and dry (non-effusive). FIP can also affect the eyes and central nervous system. In this case, we are talking about the ocular or neurological form of FIP. You can find more info practically on this whole portal, as it is entirely dedicated to FIP and its treatment.

Is FIP contagious?

No. The coronavirus is highly contagious and most cats will be exposed to it at some point during their life. FCoV is shed through feces, so cats who share a litter box or groom one another are exposed to the benign form of the virus. Cats who have a healthy immune system will pass the coronavirus with little to no issue other than a bout of diarrhea and/or cold-like symptoms.

Cats who have a weakened or not fully developed immune system may not be able to pass the coronavirus, and the virus mutates into FIP. Once mutated into FIP, the virus is no longer contagious.

There is believed to be a genetic component with FIP, so biological litter mates may share the same genetic predisposition that allows FCoV to mutate. A family history of FIP does unfortunately increase the likelihood that siblings will develop FIP.

How is FIP diagnosed?

There is no unambiguous test that definitely confirms the diagnosis of FIP. Diagnosis is usually the result of a combination of clinical signs, blood tests, titer results, the presence of fluid in the abdominal or thoracic cavity, and other specific tests. Check page of FIP diagnostics .

What is GS-441524 ?

GS-441524 (abbreviated GS) is an experimental antiviral drug (nucleoside analog) used during field trial led by Dr. Niels Pedersen at UC Davis in 2017.

The drug exists in injectable and oral form under the names of various brands.

How much does it cost to treat one cat?

The treatment lasts 84 days. The cheapest treatment is by injection, where at current prices, depending on the brand of the drug, you can get at a basic dose of the active substance of 6 mg/kg per 250-400 € (cca 6700-10500 Kč) per 1 kg live weight of the cat for the entire duration of treatment. For tablets, you have to reckon with 450-550 € (cca 12000-14500 Kč) per 1 kg live weight of the cat for the entire duration of treatment. You never have to buy medication for the whole treatment at once. With a possible conservative dosage of 5 mg/kg, it is possible to save approx. 17%.

How long does the treatment last?

Recommended duration of treatment based on the original clinical study of Dr. Pedersen lasts for at least 12 weeks of subcutaneous injections.

After twelve weeks, blood testing is recommended and the clinical status of the cat should be assessed to determine whether treatment should be continued.